The pharmacological effects of senna
【Pharmacological effects】
1. Purgative effect: The efficacy of senna leaf is strongest with diterpenoid quinones such as senna diarrhea A, followed by diarrhea, free phlegm may be oxidized through digestive tract, so the effect is weak; combined type Anthraquinones have a protective effect. When they reach the large intestine, they are decomposed into bacteria by enzymes or enzymes, stimulate the large intestine, increase the tension and peristalsis, and reduce water absorption and cause diarrhea (see Rhubarb).
2. Anti-fungus: 25% water inoculation with tube method, inhibition of microsporidium auricularia, star nocardiella.
3. Hemostasis: Senna total 200mg/kg intraperitoneal injection, capillary tube method has no effect on mice.
4. Toxicity: Intraperitoneal injection of Senna leaves, the LD50 for mice is 1.141g/kg.
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